The secrets of life lie in the molecular flexibility.

Welcome to Prof. Mariusz Jaremko's research group, the

Flexible Systems Lab!

Our research group works mainly on metabolites which are important for human health, and our current main focus in this discipline is oriented towards food, food safety, food quality, and food fraud by utilizing state-of-the-art instrumentation in metabolomics studies. We are also working on aggregation of amylin, a biological peptide that is connected tightly with diabetes II, a disease that is closely related to unhealthy diets. So, food science and the consequences of the food we eat are one of the main areas which the group Flexible Systems investigates. We are also working to develop methods and pulse programs in Nuclear Magnetic Resonance (NMR) that allow us to uncover obscured metabolites and to detect them at lower concentrations, in order to understand metabolic pathways better. 


Why the name Flexible Systems?

It's simple; because metabolites, as well as amylin and its analogues, are very flexible systems i.e. amylin does not have a defined 3D structure, and in the case of the small molecules and metabolites we study, while they do have defined structures, they often exhibit very high levels of dynamic flexibility due to their size.

Latest Publications

Compounds with antiinflammatory activity and methods of use thereof
Patent Year: 2021
Authors: Carlos M. Duarte, Susana Agusti, Mariusz Jaremko, Lukasz Jaremko, Vaileios Roussis, Esfstathia Ioannou, Aikaterini Koutsaviti, Christos Tsatasnis, Sotirios Kampranis, Maria Daskalaki
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Extraction and Fractionation of Prokinetic Phytochemicals from Chrozophora tinctoria and Their Bioactivities
Original Article Year: 2022 DOI:https://doi.org/10.3390/molecules27134321
Authors: Arshad Iqbal, Ayaz Ali Sher, Naveed Muhammad, Syed Lal Badshah, Abdul-Hamid Emwas, Mariusz Jaremko
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Important Flavonoids and Their Role as a Therapeutic Agent
Review Article Year: 2020 DOI:https://doi.org/10.3390/molecules25225243
Authors: Asad Ullah, Sidra Munir, Syed Lal Badshah, Noreen Khan, Lubna Ghani, Benjamin Gabriel Poulson, Abdul-Hamid Emwas, Mariusz Jaremko
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